Left atrial appendage closure guided by fusion of 3D computational modelling on real-time fluoroscopy: A multicenter experience.

Philippe Garot¹, Emmanuel Gall², Sandra Zendjebil³, Pedro Cepas-Guillén⁴, Xavier Iriart⁵, Bruno Farah⁶, Carsten Skurk⁷, Alexandre Gautier³, Cheuk Bong Ho⁸, Alessandra M Bavo⁹, Régis Vaillant¹⁰, Jérôme Horvilleur³, Xavier Freixa⁴, Jacqueline Saw¹¹, Ole de Backer⁸

¹Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France. Electronic address: p.garot@angio-icps.com.

²Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France; Université Paris-Cité, Department of Cardiology, University Hospital of Lariboisiere, (Assistance Publique des Hôpitaux de Paris, AP-HP), 75010 Paris, France; Inserm MASCOT - UMRS 942, University Hospital of Lariboisiere, 75010 Paris, France; MIRACL.ai laboratory, Multimodality Imaging for Research and Artificial Intelligence Core Laboratory, University Hospital of Lariboisiere (AP-HP), 75010 Paris, France.

³Institut Cardiovasculaire Paris Sud (ICPS), Hôpital Jacques Cartier, Ramsay-Santé, Massy, France.

⁴Institut Clínic Cardiovascular, Hospital Clínic, Barcelona, Spain.

⁵Department of Pediatric and Adult Congenital Cardiology, Hôpital Cardiologique du Haut-Lévêque, CHU de Bordeaux, Bordeaux-Pessac, France.

⁶Clinique Pasteur, Toulouse, France.

⁷Deutches Herzzentrum des Charite (DHZC), Department of Cardiology, Angiology and Intensive Care Medicine, Campus Benjamin Franklin, Berlin, Germany.

⁸Rigshospitalet, Copenhagen University Hospital, Copenhagen, Denmark.

⁹FEops NV, Ghent, Belgium.

¹⁰General Electric Healthcare, Buc, France.

¹¹Division of Cardiology, Vancouver General Hospital, Vancouver, British Columbia, Canada.

PubMed DOI

Abstract

BACKGROUND: Patient-specific 3-dimensional (3D) computational modelling offers a tailored approach with promising results, but experience using digital-twin fusion on real-time fluoroscopy to guide left atrial appendage closure (LAAC) is unreported. OBJECTIVES: To assess whether LAAC guided by fusion of a 3D computational model on real-time fluoroscopy is safe and effective. METHODS: We included…

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