Peer-Reviewed Publication
Pathol Res Pract2024;261155480.September 1, 2024Journal Article

A decision support system for the detection of cutaneous fungal infections using artificial intelligence.

Naama Rappoport1, Gil Goldinger2, Assaf Debby3, Yosef Molchanov4, Yoash Barak5, Jacob Gildenblat6, Ofir Hadar7, Chen Sagiv8, Aviv Barzilai9
1Department of Dermatology, Rabin Medical Center, Beilinson Hospital, Petach Tikva, Israel; Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel; Department of Dermatology, Sheba Medical Center, Ramat Gan, Israel; Faculty of Medicine, Tel Aviv University, Israel. Electronic address: nimarap123@gmail.com.
2Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel. Electronic address: Gil.Goldinger@sheba.health.gov.il.
3Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel. Electronic address: Assaf.Debby@sheba.health.gov.il.
4Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel. Electronic address: Yossef.Molchanov@sheba.health.gov.il.
5Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel. Electronic address: Yoash.Barak@sheba.health.gov.il.
6DeePathology Ltd., HaTidhar 5, Ra'anana, Israel. Electronic address: jacob@deepathology.ai.
7DeePathology Ltd., HaTidhar 5, Ra'anana, Israel. Electronic address: ofir@deepathology.ai.
8DeePathology Ltd., HaTidhar 5, Ra'anana, Israel. Electronic address: chen@deepathology.ai.
9Institute of Pathology, Sheba Medical Center, Ramat Gan, Israel; Department of Dermatology, Sheba Medical Center, Ramat Gan, Israel; Faculty of Medicine, Tel Aviv University, Israel. Electronic address: Aviv.Barzilai@sheba.health.gov.il.

Abstract

Cutaneous fungal infections are one of the most common skin conditions, hence, the burden of determining fungal elements upon microscopic examination with periodic acid-Schiff (PAS) and Gomori methenamine silver (GMS) stains, is very time consuming. Despite some morphological variability posing challenges to training artificial intelligence (AI)-based solutions, these structures are favored potent…

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