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Peer-Reviewed Publication
J Affect Disord2024;349494-501.March 15, 2024Randomized Controlled Trial

Therapist-supported digital mental health intervention for depressive symptoms: A randomized clinical trial.

Valerie L Forman-Hoffman1, Samuel Sihvonen2, Joseph Wielgosz3, Eric Kuhn4, Benjamin W Nelson5, Nicholas C Peiper6, Christine E Gould7
1Meru Health, San Mateo, CA, USA; Department of Epidemiology, University of Iowa, Iowa City, IA, USA.
2Meru Health, San Mateo, CA, USA.
3National Center for PTSD Dissemination and Training Division, VA Palo Alto Healthcare System, Palo Alto, CA, USA.
4National Center for PTSD Dissemination and Training Division, VA Palo Alto Healthcare System, Palo Alto, CA, USA; Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.
5Meru Health, San Mateo, CA, USA; Department of Psychology and Neuroscience, University of North Carolina at Chapel Hill, Chapel Hill, NC, USA.
6Meru Health, San Mateo, CA, USA; Department of Epidemiology and Population Health, University of Louisville, Louisville, KY, USA.
7Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA; Geriatric Research Education and Clinical Center, VA Palo Alto Health Care System, Palo Alto, CA, USA. Electronic address: cegould@stanford.edu.

Abstract

Depression is a chronic and debilitating mental disorder. Despite the existence of several evidence-based treatments, many individuals suffering from depression face myriad structural barriers to accessing timely care which may be alleviated by digital mental health interventions (DMHI). Accordingly, this randomized clinical trial (ClinicalTrials.gov: NCT04738084) investigated the efficacy of a ne…

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