Opportunistic Screening of Low Bone Mineral Density From Standard X-Rays.

Alexander Bilbily¹, Catriona A Syme², Jonathan D Adachi³, Claudie Berger⁴, Suzanne N Morin⁵, David Goltzman⁵, Mark D Cicero⁶

¹16 Bit Inc, Toronto, Ontario, Canada; Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada.

²16 Bit Inc, Toronto, Ontario, Canada.

³Division of Rheumatology, Department of Medicine, McMaster University, Hamilton, Ontario, Canada.

⁴Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada.

⁵Research Institute of the McGill University Health Centre, Montreal, Quebec, Canada; Department of Medicine, McGill University, Montreal, Quebec, Canada.

⁶16 Bit Inc, Toronto, Ontario, Canada; True North Imaging, Toronto, Ontario, Canada. Electronic address: mark@16bit.ai.

PubMed DOI

Abstract

BACKGROUND: Osteoporosis, characterized by loss of bone mineral density (BMD), is underscreened. Osteoporosis and low bone mass are diagnosed by a BMD T-score ≤ -2.5, and between -1.0 and -2.5, respectively, at the femoral neck or lumbar vertebrae (L1-4), using dual energy x-ray absorptiometry (DXA). The ability to estimate BMD at those anatomic sites from standard radiographs would enable opportu…

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