Peer-Reviewed Publication
NPJ Digit Med2023;6(1):184.October 4, 2023Journal Article

Autonomous artificial intelligence increases real-world specialist clinic productivity in a cluster-randomized trial.

Michael D Abramoff1,2,3,4,5, Noelle Whitestone6, Jennifer L Patnaik6,7, Emily Rich6,8, Munir Ahmed9, Lutful Husain9, Mohammad Yeadul Hassan9, Md Sajidul Huq Tanjil10, Dena Weitzman11, Tinglong Dai12,13,14, Brandie D Wagner7,15, David H Cherwek6, Nathan Congdon6,8,16, Khairul Islam10
1University of Iowa, Iowa City, Iowa, USA. michael-abramoff@uiowa.edu.
2Digital Diagnostics Inc, Coralville, Iowa, USA. michael-abramoff@uiowa.edu.
3Iowa City Veterans Affairs Medical Center, Iowa City, Iowa, USA. michael-abramoff@uiowa.edu.
4Department of Biomedical Engineering, The University of Iowa, Iowa City, USA. michael-abramoff@uiowa.edu.
5Department of Electrical and Computer Engineering, The University of Iowa, Iowa City, Iowa, USA. michael-abramoff@uiowa.edu.
6Orbis International, New York, New York, USA.
7Department of Ophthalmology, University of Colorado School of Medicine, Aurora, Colorado, USA.
8Centre for Public Health, Queen's University Belfast, Belfast, UK.
9Orbis Bangladesh, Dhaka, Bangladesh.
10Deep Eye Care Foundation, Rangpur, Bangladesh.
11Digital Diagnostics Inc, Coralville, Iowa, USA.
12Carey Business School, Johns Hopkins University, Baltimore, Maryland, USA.
13Hopkins Business of Health Initiative, Johns Hopkins University, Baltimore, Maryland, USA.
14School of Nursing, Johns Hopkins University, Baltimore, Maryland, USA.
15Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado, USA.
16Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Abstract

Autonomous artificial intelligence (AI) promises to increase healthcare productivity, but real-world evidence is lacking. We developed a clinic productivity model to generate testable hypotheses and study design for a preregistered cluster-randomized clinical trial, in which we tested the hypothesis that a previously validated US FDA-authorized AI for diabetic eye exams increases clinic productivi…

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