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JCO Precis Oncol2023;7e2100489.April 1, 2023Journal Article

Complete Remission of Widely Metastatic Human Epidermal Growth Factor Receptor 2-Amplified Pancreatic Adenocarcinoma After Precision Immune and Targeted Therapy With Description of Sequencing and Organoid Correlates.

Daniel A King1, Amber R Smith2, Gino Pineda3, Michitaka Nakano4, Flavia Michelini5, S Peter Goedegebuure6, Sheeno Thyparambil7, Wei-Li Liao7, Aaron McCormick4, Jihang Ju4, Michele Cioffi8, Xiuli Zhang6, Jasreet Hundal6, Malachi Griffith9, Carla Grandori10, Maddy Pollastro10, Rachele Rosati10, Astrid Margossian10, Payel Chatterjee10, Trevor Ainge10, Marta Flory11, Paolo Ocampo12, Lee-May Chen13, George A Poultsides14, Ari D Baron15, Daniel T Chang16, Joseph M Herman17, William E Gillanders6, Haeseong Park18, William A Hoos19, Mike Nichols20, George A Fisher3, Calvin J Kuo3
1Northwell Health Cancer Institute and Feinstein Institute of Research, Lake Success, NY.
2Xilis Corporation, Durham, NC.
3Stanford Cancer Institute, Stanford, CA.
4Department of Medicine, Divisions of Hematology and Oncology, Stanford University School of Medicine, Stanford, CA.
5Memorial Sloan Kettering Cancer Center, NY, NY.
6Department of Surgery, Washington University School of Medicine in St Louis, St Louis, MO.
7Mprobe, Inc, Rockville, MD.
8Cornell University, School of Medicine, New York, NY.
9Department of Medicine, Washington University School of Medicine, St Louis, MO.
10SEngine Precision Medicine, Seattle, WA.
11Department of Radiology, Stanford University, Stanford, CA.
12Personalized Healthcare, Genentech, Inc, South San Francisco, CA.
13Department of Gynecologic Oncology, University of California at San Francisco, San Francisco, CA.
14Department of Surgery, Section of Surgical Oncology, Stanford University, Stanford, CA.
15Division of Hematology Oncology, California Pacific Medical Center, San Francisco, CA.
16Department of Radiation Oncology, Stanford Cancer Institute, Stanford, CA.
17Department of Radiation Oncology and Northwell Health Cancer Institute, Lake Success, NY.
18Department of Medicine, Division of Oncology, Washington University School of Medicine in St Louis.
19xCures Inc, Oakland, CA.
20Independent Clinician, Saratoga, CA.
PubMed PMC DOI PDF

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