Health AI Central
Peer-Reviewed Publication
MicroPubl Biol2023;2023January 1, 2023Journal Article

BY4741 cannot enter quiescence from rich medium.

Shawna Miles1, Cameron Lee2, Linda Breeden1
1Basic Science, Fred Hutchinson Cancer Center, Seattle, Washington, United States.
2Tune Therapeutics, 1930 Boren Ave., Seattle, Washington, United States.
PubMed PMC DOI PDF

Abstract

In rich medium, W303 Saccharomyces cerevisiae begins to accumulate in G1 an hour before it exhausts the available glucose. It undergoes one more asymmetrical cell division, then stops dividing in G1. In contrast, BY4741, stops dividing four hours before glucose exhaustion, at one-fourth the cell density achieved by W303. There is no asymmetrical cell division and only 50% of the cells arrest in G1…

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