MRI-based synthetic CT in the detection of knee osteoarthritis: Comparison with CT.

Saeed Arbabi^1,2, Wouter Foppen³, Willem Paul Gielis^2,3, Marijn van Stralen⁴, Mylène Jansen⁵, Vahid Arbabi^2,6, Pim A de Jong³, Harrie Weinans^2,7, Peter Seevinck^1,4

¹Image Sciences Institute, University Medical Center Utrecht, Utrecht, The Netherlands.

²Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands.

³Department of Radiology, University Medical Center Utrecht, Utrecht, The Netherlands.

⁴MRIguidance B.V., Utrecht, The Netherlands.

⁵Rheumatology & Clinical Immunology, University Medical Center Utrecht, Utrecht, The Netherlands.

⁶Department of Mechanical Engineering, Faculty of Engineering, Orthopaedic-Biomechanics Research Group, Birjand, Iran.

⁷Department of Biomechanical Engineering, Delft University of Technology (TU Delft), Delft, The Netherlands.

PubMed DOI

Abstract

Magnetic resonance Imaging is the gold standard for assessment of soft tissues; however, X-ray-based techniques are required for evaluating bone-related pathologies. This study evaluated the performance of synthetic computed tomography (sCT), a novel MRI-based bone visualization technique, compared with CT, for the scoring of knee osteoarthritis. sCT images were generated from the 3T T1-weighted g…

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