A review on investigation of the basic contrast mechanism underlying multidimensional diffusion MRI in assessment of neurological disorders.

Nisha Syed Nasser¹, Sriram Rajan², Vasantha Kumar Venugopal³, Samo Lasič⁴, Vidur Mahajan³, Harsh Mahajan⁵

¹CARPL.ai, New Delhi, India. Electronic address: nisha.nasser@carpl.ai.

²Department of Radiology, Mahajan Imaging, New Delhi, India.

³CARPL.ai, New Delhi, India.

⁴Random Walk Imaging AB, Lund, Sweden.

⁵CARPL.ai, New Delhi, India; Department of Radiology, Mahajan Imaging, New Delhi, India.

PubMed DOI

Abstract

INTRODUCTION: Multidimensional diffusion MRI (MDD MRI) is a novel diffusion technique that uses advanced gradient waveforms for microstructural tissue characterization to provide information about average rate, anisotropy and orientation of the diffusion and to disentangle the signal fraction from specific cell types i.e., elongated cells, isotropic cells and free water. AIM: To review the diagno…

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