Peer-Reviewed Publication
Circ Cardiovasc Imaging2022;15(6):e013987.June 1, 2022Journal Article
Accuracy and Reproducibility of Myocardial Blood Flow Quantification by Single Photon Emission Computed Tomography Imaging in Patients With Known or Suspected Coronary Artery Disease.
Ana Carolina do A H de Souza1, Hendrik J Harms1, Laurel Martell1, Courtney Bibbo1,2, Meagan Harrington1, Kyle Sullivan1, Jon Hainer1, Sharmila Dorbala1, Ron Blankstein1, Viviany R Taqueti1, Marie Foley Kijewski1, Mi-Ae Park1, Alejandro Meretta3, Christopher Breault1, Nathaniel Roth2, Alexis Poitrasson-Rivière4, Prem Soman5, Grant T Gullberg6, Marcelo F Di Carli1
1Cardiovascular Imaging Program, Departments of Medicine and Radiology, Brigham and Women's Hospital, Boston, MA (A.C.d.A.H.d.S., H.J.H., L.M., C.B., M.H., K.S., J.H., S.D., R.B., V.R.T., M.F., M.-A.P., M.F.D.C.).
2Spectrum Dynamics Medical, Caesarea, Israel (C.B., N.R.).
3Instituto Cardiovascular de Buenos Aires, Buenos Aires, Argentina (A.M.).
4INVIA Medical Imaging Solutions, Ann Harbor' MI (A.P.-R.).
5Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA (P.S.).
6Department of Radiology and Biomedical Imaging, University of California San Francisco, San Francisco, CA (G.T.G.).
Abstract
BACKGROUND: Single photon emission computed tomography (SPECT) has limited ability to identify multivessel and microvascular coronary artery disease. Gamma cameras with cadmium zinc telluride detectors allow the quantification of absolute myocardial blood flow (MBF) and myocardial flow reserve (MFR). However, evidence of its accuracy is limited, and of its reproducibility is lacking. We aimed to v…
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