Peer-Reviewed Publication
Sci Adv2021;7(52):eabl4146.December 24, 2021Journal Article
At-home wireless monitoring of acute hemodynamic disturbances to detect sleep apnea and sleep stages via a soft sternal patch.
Nathan Zavanelli1,2, Hojoong Kim1,2, Jongsu Kim1,2, Robert Herbert1,2, Musa Mahmood1,2, Yun-Soung Kim1,2, Shinjae Kwon1,2, Nicholas B Bolus3, F Brennan Torstrick3, Christopher S D Lee3, Woon-Hong Yeo1,2,4,5
1George W. Woodruff School of Mechanical Engineering, College of Engineering, Georgia Institute of Technology, Atlanta, GA 30332, USA.
2Center for Human-Centric Interfaces and Engineering at the Institute for Electronics and Nanotechnology, Georgia Institute of Technology, Atlanta, GA 30332, USA.
3Huxley Medical Inc., Atlanta, GA 30318, USA.
4Wallace H. Coulter Department of Biomedical Engineering, Parker H. Petit Institute for Bioengineering and Biosciences, Georgia Institute of Technology and Emory University, Atlanta, GA 30332, USA.
5Institute for Robotics and Intelligent Machines, Neural Engineering Center, Flexible and Wearable Electronics Advanced Research, Institute for Materials, Georgia Institute of Technology, Atlanta, GA 30332, USA.
Abstract
Obstructive sleep apnea (OSA) affects more than 900 million adults globally and can create serious health complications when untreated; however, 80% of cases remain undiagnosed. Critically, current diagnostic techniques are fundamentally limited by low throughputs and high failure rates. Here, we report a wireless, fully integrated, soft patch with skin-like mechanics optimized through analytical…
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