Impact of Integrating Rumke Statistics to Assist with Choosing Between Automated Hematology Analyzer Differentials vs Manual Differentials.

Laura Stephens¹, Wendy Hintz-Prunty¹, Hans-Inge Bengtsson², James A Proudfoot³, Sandip Pravin Patel^4,5, H Elizabeth Broome^1,4

¹Department of Pathology, University of California, San Diego, San Diego, CA.

²CellaVision AB, Ideon Science Park, Lund, Sweden.

³Department of Clinical and Translational Research Institute, University of California, San Diego, San Diego, CA.

⁴Moores Cancer Center, University of California, San Diego, San Diego, CA.

⁵Department of Medicine, University of California, San Diego, San Diego, CA.

PubMed DOI

Abstract

BACKGROUND: To optimize precision of nucleated blood cell counting, the clinical laboratory scientist should post the automated differential rather than the manual differential if the former is within the 95% CI of the latter, as determined by the "Rumke statistic." The objective of this study was to determine the potential impact of real-time, computer-assisted use of Rumke statistics for more ju…

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