Peer-Reviewed Publication
Nat Med2020;26(1):77-82.January 1, 2020Journal Article
Automated opportunistic osteoporotic fracture risk assessment using computed tomography scans to aid in FRAX underutilization.
Noa Dagan1,2,3, Eldad Elnekave4,5, Noam Barda6,7,8, Orna Bregman-Amitai5, Amir Bar5, Mila Orlovsky5, Eitan Bachmat7, Ran D Balicer6,8
1Clalit Research Institute, Clalit Health Services, Tel Aviv, Israel. noada@clalit.org.il.
2Department of Computer Science, Ben-Gurion University, Beer Sheva, Israel. noada@clalit.org.il.
3School of Public Health, Ben-Gurion University, Beer Sheva, Israel. noada@clalit.org.il.
4Department of Diagnostic Radiology, Rabin Medical Center, Beilinson Hospital, Petah Tikva, Israel.
5Zebra Medical Vision, Ltd, Shefayim, Israel.
6Clalit Research Institute, Clalit Health Services, Tel Aviv, Israel.
7Department of Computer Science, Ben-Gurion University, Beer Sheva, Israel.
8School of Public Health, Ben-Gurion University, Beer Sheva, Israel.
Abstract
Methods for identifying patients at high risk for osteoporotic fractures, including dual-energy X-ray absorptiometry (DXA)1,2 and risk predictors like the Fracture Risk Assessment Tool (FRAX)3-6, are underutilized. We assessed the feasibility of automatic, opportunistic fracture risk evaluation based on routine abdomen or chest computed tomography (CT) scans. A CT-based predictor was created using…
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