Share:
Peer-Reviewed Publication
J Nucl Cardiol2021;28(4):1477-1486.August 1, 2021Journal Article

Quantification of myocardial blood flow by CZT-SPECT with motion correction and comparison with 15O-water PET.

Yuka Otaki1, Osamu Manabe1,2, Robert J H Miller1, Alain Manrique3, Catherine Nganoa3, Nathaniel Roth4, Daniel S Berman1, Guido Germano1, Piotr J Slomka5, Denis Agostini3
1Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
2Department of Nuclear Medicine, Hokkaido University of Graduate School of Medicine, Sapporo, Japan.
3Department of Nuclear Medicine, CHU Cote de Nacre, Normandy University, Caen, France.
4Spectrum Dynamics Medical Ltd., Caesarea, Israel.
5Departments of Imaging and Medicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA. slomkap@cshs.org.

Abstract

BACKGROUND: We compared quantification of MBF and myocardial flow reserve (MFR) with a 99mTc-sestamibi CZT-SPECT to 15O-water PET. METHODS: SPECT MBF for thirty patients in the WATERDAY study was re-analyzed by QPET software with motion correction and optimal placement of the arterial input function. 15O-water PET MBF was re-quantified using dedicated software. Inter-operator variability was asse…

Create a free account to keep reading

Free members get 10 full research views every month across publications, clinical trials, FDA clearances, adverse events, and NIH grants. No credit card required.

Want unlimited research access? See Pro plans

Data Accuracy Notice: Research intelligence on Health AI Central is aggregated from public sources (PubMed, ClinicalTrials.gov, FDA, NIH, CMS, and others) and refreshed nightly. Classifications and derived metrics are produced by automated methods described in our Methodology. We recommend verifying critical data points against the primary sources before making decisions.