Peer-Reviewed Publication
Radiology2019;292(3):564-572.September 1, 2019Journal Article
Optoacoustic Imaging and Gray-Scale US Features of Breast Cancers: Correlation with Molecular Subtypes.
Basak E Dogan1, Gisela L G Menezes1, Reni S Butler1, Erin I Neuschler1, Roger Aitchison1, Philip T Lavin1, F Lee Tucker1, Stephen R Grobmyer1, Pamela M Otto1, A Thomas Stavros1
1From the Department of Diagnostic Radiology, The University of Texas Southwestern Medical Center, 2201 Inwood Rd, Dallas, TX 75390-8585 (B.E.D.); Department of Radiology, University of Texas Health Science Center at San Antonio, San Antonio, TX (G.L.G.M., P.M.O., A.T.S.); Seno Medical Instruments, San Antonio, TX (G.L.G.M., A.T.S.); Department of Radiology and Biomedical Imaging, Yale School of Medicine, New Haven, CT (R.S.B.); Department of Radiology, Assistant Professor, Northwestern University Feinberg School of Medicine, Chicago, IL (E.I.N.); Boston Biostatistics Research Foundation, Boston, MA (R.A., P.T.L); Virginia Biomedical Laboratories, LLC, Wirtz, VA (F.L.T.); and Department of Surgical Oncology, Cleveland Clinic, Cleveland, OH (S.R.G.).
Abstract
Background Optoacoustic imaging can assess tumor hypoxia coregistered with US gray-scale images. The combination of optoacoustic imaging and US may have a role in distinguishing breast cancer molecular subtypes. Purpose To investigate whether optoacoustic US feature scores correlate with breast cancer molecular subtypes. Materials and Methods A total of 1972 women (with a total of 2055 breast mass…
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