Peer-Reviewed Publication
PLoS One2019;14(6):e0215267.January 1, 2019Journal Article
Muscle fiber hypertrophy in response to 6 weeks of high-volume resistance training in trained young men is largely attributed to sarcoplasmic hypertrophy.
Cody T Haun1, Christopher G Vann2, Shelby C Osburn2, Petey W Mumford2, Paul A Roberson2, Matthew A Romero2, Carlton D Fox2, Christopher A Johnson3, Hailey A Parry2, Andreas N Kavazis2, Jordan R Moon4, Veera L D Badisa5, Benjamin M Mwashote5, Victor Ibeanusi5, Kaelin C Young2,6, Michael D Roberts2,6
1Department of Exercise Science, LaGrange College, LaGrange, GA, United States of America.
2School of Kinesiology, Auburn University, Auburn, AL, United States of America.
3School of Medicine, University of Alabama Birmingham, Birmingham, AL, United States of America.
4Impedimed, Carlsbad, CA, United States of America.
5School of the Environment, Florida A&M University, Tallahassee, FL, United States of America.
6Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine-Auburn Campus, Auburn, AL, United States of America.
Abstract
Cellular adaptations that occur during skeletal muscle hypertrophy in response to high-volume resistance training are not well-characterized. Therefore, we sought to explore how actin, myosin, sarcoplasmic protein, mitochondrial, and glycogen concentrations were altered in individuals that exhibited mean skeletal muscle fiber cross-sectional area (fCSA) hypertrophy following 6 weeks of high-volume…
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