Pre-training Skeletal Muscle Fiber Size and Predominant Fiber Type Best Predict Hypertrophic Responses to 6 Weeks of Resistance Training in Previously Trained Young Men.

Cody T Haun^1,2, Christopher G Vann¹, C Brooks Mobley¹, Shelby C Osburn¹, Petey W Mumford¹, Paul A Roberson¹, Matthew A Romero¹, Carlton D Fox¹, Hailey A Parry¹, Andreas N Kavazis¹, Jordan R Moon³, Kaelin C Young^1,4, Michael D Roberts^1,4

¹School of Kinesiology, Auburn University, Auburn, AL, United States.

²Department of Exercise Science, LaGrange College, LaGrange, GA, United States.

³Impedimed, Inc., Carlsbad, CA, United States.

⁴Department of Cell Biology and Physiology, Edward Via College of Osteopathic Medicine - Auburn Campus, Auburn, AL, United States.

PubMed PMC DOI PDF

Abstract

Limited evidence exists regarding differentially expressed biomarkers between previously-trained low versus high hypertrophic responders in response to resistance training. Herein, 30 college-aged males (training age 5 ± 3 years; mean ± SD) partook in 6 weeks of high-volume resistance training. Body composition, right leg vastus lateralis (VL) biopsies, and blood were obtained prior to training (P…

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