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Peer-Reviewed Publication
Magn Reson Med2017;78(3):963-975.September 1, 2017Journal Article

Spectrally selective three-dimensional dynamic balanced steady-state free precession for hyperpolarized C-13 metabolic imaging with spectrally selective radiofrequency pulses.

Hong Shang1,2, Subramaniam Sukumar1, Cornelius von Morze1, Robert A Bok1, Irene Marco-Rius1, Adam Kerr3, Galen D Reed4, Eugene Milshteyn1,2, Michael A Ohliger1, John Kurhanewicz1,2, Peder E Z Larson1,2, John M Pauly3, Daniel B Vigneron1,2
1Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, USA.
2UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, San Francisco and University of California, Berkeley, California, USA.
3Electrical Engineering, Stanford University, Stanford, California, USA.
4HeartVista, Menlo Park, California, USA.

Abstract

PURPOSE: Balanced steady-state free precession (bSSFP) sequences can provide superior signal-to-noise ratio efficiency for hyperpolarized (HP) carbon-13 (13 C) magnetic resonance imaging by efficiently utilizing the nonrecoverable magnetization, but managing their spectral response is challenging in the context of metabolic imaging. A new spectrally selective bSSFP sequence was developed for fast…

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